The Up in the Air star has taken on the unpleasant role of tyrant Captain Bligh from Mutiny on the Bounty, while Pitt has opted to do his best impression of horror film actor Peter Lorre and portray Eraserhead's Henry Spencer for this week's (begs12Dec11) issue of The New York Times Magazine.
Clooney says, "I picked Captain Bligh because I liked his hat. Bad guys don't think they're bad guys. In film, the best evil performances are when the actor remembers that."
Oldman dons full face paint to depict a menacing dummy and The Girl with the Dragon Tattoo actress Mara dresses up as sociopath Alex from A Clockwork Orange.
Kirsten Dunst, Mia Wasikowska, Viola Davis, Ryan Gosling and Glenn Close have also taken part in the Touch of Evil shoot.