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Feb 03, 2012 | 4:00am EST

Twilight star Michael Sheen has replaced fellow Brit Paul Bettany as 1960s sex expert William Masters in a racy new U.S. cable series. The Welsh star will lead the cast of Masters of Sex for Showtime opposite Lizzy Kaplan, who will play Masters' partner Virginia Johnson. Shakespeare in Love's John Madden is slated to direct.

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