The new mum and Cruel Intentions star created the SB by Selma Blair range, which is composed of four different styles of unique leather and suede satchels.
She tells Us Weekly, "They're timeless and affordable. They can be worn for years, so it's worth the few hundred bucks!"
Prices start at $160 (£100) and a portion of the proceeds will benefit the Lange Foundation, a Los Angeles no-kill animal shelter dedicated to saving homeless and abandoned pets.
It's a busy time for Blair, who has just landed a leading role in Charlie Sheen's new TV sitcom Anger Management - as his character's therapist-turned-lover.