The Green Card star has been pals with the revolutionary for 20 years and travelled to the Caribbean island republic in 2006 to attend his lavish birthday party.
Depardieu, who has even invested in an oil field in Cuba, has now opened up about the unlikely partnership, insisting he loves hunting with Castro and younger brother Raul.
The actor tells U.K. chat show host Graham Norton, "I met him (in) 1992 when I made him pate. He loves to eat also, and is very curious about food. He is a friend and I go hunting with him and with Raul. They know everything about everything and they are normal people."