Stiller and Jackson join a star-studded cast on the British show, which will also feature homegrown actors Jude Law and Kate Winslet.
Each big name actor will be cast in their own episode of the BBC comedy series, about film extras chasing their big break.
Gervais says, "I am delighted. Ben is the finest comedy actor of the moment, while Samuel is a legend. They will both play extreme and twisted versions of themselves.
"The success of The Office in America means it is much easier for me to approach such big stars.
"Ben is a huge fan of The Office. He wanted to produce the U.S. version but unfortunately didn't have time. I had lunch with him and he said he'd love us to work together."
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