Cruise--who claims to have helped people fight drug addictions through his controversial Scientology religion--recently attacked the Suddenly Susan star for becoming dependant on Paxil, following the birth of her daughter Rowan.
But Shields is disgusted by the Top Gun star's "dangerous" comments and took a swipe at his Scientology beliefs, by saying she wouldn't take advice from someone who devotes his life to creatures from outer space.
She fumes, "His comments are dangerous. He should stick to saving the world from aliens.
Shields is currently weaning herself off her medication so she and husband Chris Henchy can have another child.
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