Desert island drama Lost beat the Housewives, House, Rescue Me and Veronica Mars to pick up Outstanding New Program trophy, as well as Outstanding Achievement in Drama, at the star-studded ceremony in the Beverly Hilton hotel, which was hosted by Scots funnyman Craig Ferguson.
Desperate Housewives creator Marc Cherry was ecstatic when his drama was named Program of the Year, saying, "A lot of writers in Hollywood go around and they say, 'Oh, I don't care what the critics say, I don't care about critics.' I must tell you now, I care desperately what you guys say. It matters to me greatly."
The team behind were Arrested Development were delighted with their Outstanding Achievement in Comedy gong, after the comedy narrowly avoided being cancelled by the Fox network after falling ratings earlier this year.
Comedian Bob Newhart was also honored with a lifetime achievement accolade.
The full list of winners is:
Program of the Year: Desperate Housewives
Outstanding Achievement in Comedy: Arrested Development
Outstanding Achievement In Drama: Lost
Outstanding Achievement Movies, Mini-Series and Specials: The Office Special
Outstanding New Program of the Year: Lost
Individual Achievement in Comedy: Jon Stewart for The Daily Show With Jon Stewart
Individual Achievement in Drama: Hugh Laurie for House
Outstanding Achievement in Children's Programming: Degrassi: The Next Generation
Outstanding Achievement in News and Information: Frontline
Heritage Award: Nightline
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