Photographer Art Streiber shot the star-studded group snap for Vanity Fair and admits he was cool, calm and collected until DiCaprio arrived.
He recalls, "He looked up at the stage and he said, 'This is epic'."
And the magic moment wasn't lost on Charlize Theron: "There are moments in your life where you find yourself in circumstances where you just have to pinch yourself. I got to rest my hand on Harrison Ford's shoulder, while Steven Spielberg was standing next to me - not too shabby."
The shoot also features young stars like Justin Bieber and Megan Fox and Rosie Huntington-Whiteley from the Transformers movie franchise.
In total 116 superstars and movie executives turned up for the once-in-a-lifetime shoot, photographed on the soundstage that housed the Star Trek TV and movie franchises.
Star Trek captains William Shatner, Patrick Stewart and Chris Pine were part of the photograph.
Streiber admits it was a great opportunity to reunite some co-stars: "There were a lot of people who hadn't seen each other in years."