More than 32,000 people have been forced to flee the Colorado city after flames ravaged the area - and former Charmed star McGowan admits her sibling is at risk.
In a post on her Twitter.com page, she writes, "My sister lives in Colorado Springs and is probably next to evacuate... Please send good thoughts."
Pop superstar Cher also has a personal link to the disaster - she tweeted, "No! My nephew Ryan Southall is pilot there! Beautiful Colorado Springs... it's burning..."
McGowan's former TV co-star Alyssa Milano has reached out to those affected by the wildfires, writing on her own Twitter account, "My heart is wishing good things for the people of Colorado Springs."
Model Amber Rose, who spent Saturday (24Jun12) at her father's home in the city, posted an image of the devastation on Twitter and added, "My friend just sent me this pic from the mall in Colorado Springs... so scary."