Clark Gable III, 23, replaces TV personality Joey Greco as the presenter of the long-running show, which follows wives and husbands who catch and confront their adulterous partner.
Gable admits he is somewhat nervous about his new job after his predecessor Greco was famously stabbed during a heated exchange in a 2003 episode.
He says, "I do have some minor concerns about this. But I feel it's what I want to do and I can't live life in fear. I just take everything one day at a time. I can't say I'm not afraid. I am thrown into these environments.
"What I'm doing is dangerous. When you get people who are cheating on each other it gets very, very heated in some of the arguments. I'm learning slowly. I'm no Joey Greco but I do the best I can."
Cheaters creator Bobby Goldstein tells The Hollywood Reporter, "We just felt it was time to freshen up the show with a new host."