Industry speculation suggested the Daredevil star was in talks to take charge of the DC Comics franchise after Christopher Nolan insisted he was done with Batman following this summer's (12) release of The Dark Knight Rises.
The film will include an ensemble of superheroes, including the Caped Crusader, Superman, Green Lantern, Wonder Woman and The Flash.
However, Affleck, who has focused on moviemaking over acting in recent years, insists he is not in line to take the helm of the new project.
He says, "I'm not working on the Justice League. One of the problems with entertainment web sites is that they need to fill pages, and that's how rumours get started. Justice League sounds really exciting, but it's not something I'm working on."