The Pianist moviemaker will begin shooting the saucy comedy in Paris in November (12) and Polanski cannot wait to get started with his favourite actress.
He tells TheWrap.com, "I've been looking for a chance to make a film in French with Emmanuelle for a long time. Reading Venus in Fur I realised the moment had arrived."
The couple last worked together in 1999's The Ninth Gate, which starred Johnny Depp.
Nina Arianda originated the role Seigner will play in the film and won a Best Actress Tony Award last year (11) for the part.