The hotel heiress took gifts to youngsters at Children's Hospital Los Angeles and spent time carrying out arts and crafts activities with the patients.
In a post on her Twitter.com page, she writes, "Spent the day at The Children's Hospital visiting all the kids. Brought them presents & did art & crafts. Loved being with them. Feels so good to make them happy."
Hilton also urged her fans to donate to support 12-year-old Victor Castro's lymphoma battle, adding, "Met this wonderful young kid at the hospital today. Lets all help him for his fundraiser."
The reality TV star has been in a giving mood of late - she also took presents to children in an Indian orphanage during a trip to the country earlier this month (Dec12).