Apatow's latest film is a family affair as it stars not only his wife, Leslie Mann, but their two daughters - Maude,15, and Iris,10 - who reprise their roles from the comedy's prequel Knocked Up.
The sequel was nerve-wracking for Apatow as he was terrified the youngsters would suddenly decide they hate acting and walk off set, leaving him high and dry.
He says, "I'm afraid that they're gonna want to leave. Like, literally just go, 'I want to go home and watch SpongeBob! You can't make a c**ppy movie with your family. That's really embarrassing."