The Hollywood couple jetted to the West Indies with all six kids and Pitt's mum Jane to celebrate the holidays in the sun and - out of the spotlight.
And it appears the family has been having a blast at Karan's luxury Parrot Cay home, which reportedly has an infinity pool and open-air screening room for watching movies.
A source tells the New York Post, "They are at Donna's house, without Donna, and have been loving the island because it is so secluded. Angelina's taken the kids to Karan's yoga spa. They've been running around the island with no care in the world, and relaxing."
The actors aren't the only celebrities vacationing in Turks and Caicos over the festive season - Rolling Stones star Keith Richards has allegedly been spotted there with his family, as well as former model Christie Brinkley, her daughter Alexa Ray Joel, and Lost producer J.J. Abrams.