"E.R." Executive Producer John Wells confirmed Monday that Eriq La Salle will be leaving the hospital drama at the end of next season, becoming part of an alumni that includes George Clooney, Julianna Margulies, William H Macy and Gloria Reuben. Anthony Edwards has also announced that he will leave at the end of the season. Sherry Springfield, who left in 1996, is rejoining the show. The only remaining star of the series, who has continuously appeared on it since its 1994 debut, will be Noah Wyle.