After picking up the Crystal Award at the World Economic Forum in Switzerland, the Oscar winner will be feted for the work she does to eradicate AIDS through her Charlize Theron Africa Outreach Project.
The actress will be awarded the Honorary Chair of this year's Cinema for Peace Gala at the Waldorf Astoria Hotel, where she'll be awarded the Cinema for Peace Honorary Award.
Gala founder Jaka Bizilj says, "As a South African, Charlize Theron cares deeply about the human suffering of those infected, their families and friends due to HIV and AIDS. Every day thousands of people die of this disease. Charlize Theron's Africa Outreach Project contributes tremendously in the concerned areas, helping to educate children and minors about HIV and AIDS as well as to support affected persons."
Also up for major honours at the event are films by Oscar-nominated directors Michael Haneke (Amour), Ang Lee (Life of Pi), Steven Spielberg (Lincoln) and Benh Zeitlin (Beasts of the Southern Wild), who are all nominated in the Most Valuable Movie of the Year category at the gala, alongside Ben Affleck, Kathryn Bigelow, Nicholas Jarecki, Juan Antonio Bayona, Jacques Audiard and Kim Nguyen.