Actress Meg Ryan is set to reunite with her You've Got Mail and Sleepless In Seattle co-star Tom Hanks for her directorial debut Ithaca. The Captain Phillips star is executive producing the film, which is based on William Saroyan's 1943 novel The Human Comedy. In addition to directing, Ryan will star in the film alongside Sam Shepard, Melanie Griffith and her son Jack Quaid. The film chronicles the story of a teenager who sets out to become the fastest bicycle telegraph messenger in Ithaca, California during World War Two. She says, "Ithaca is a deceptively simple story, by turns stark and lyrical. It's sometimes shockingly unsentimental and yet, by some little miracle, never cynical. I am delighted to no end to bring a tale of such vibrancy and heart to the screen." The script will be penned by Hanks' Band of Brothers screenwriter Erik Jendresen, with production beginning in the summer (14). Saroyan's novel was adapted for the big screen the year the book came out. The Clarence Brown film starred Mickey Rooney, Donna Reed and Marsha Hunt. Late movie mogul Louis B. Mayer once called it his favourite movie.