The creations came under the spotlight before the Easy Rider star's death in May (10), when he filed legal papers accusing his estranged wife Victoria Duffy of stealing art pieces from him while he was battling cancer.
The collection included a portrait of the actor by Andy Warhol, and works by Robert Graham and British graffiti artist Banksy.
And now Hopper's pieces are set to go under the hammer - with the personal Warhol portrait expected to fetch $1.2 million (£770,000).
Marc Porter, chairman of auction house Christie's, says, "Dennis Hopper was the consummate creator. His pensive, personal collection of art reflected his strong, deep bonds with the artists whose work he collected."
Two sales of Hopper's pieces will take place; in November (10) and next January (11).