The star rose to fame as lovable character Joey Tribbiani in the hit U.S. sitcom in the 1990s alongside Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matthew Perry and David Schwimmer.
LeBlanc went on to film two seasons of spin-off show Joey when Friends ended in 2004, but he has failed to make a mark in the industry following the programme's cancellation.
The actor has seemingly grown tired of fans still greeting him with Joey's catchphrase "How you doin'?" and he reportedly became enraged during a London Fashion Week party on Tuesday when he heard the iconic comment, according to Britain's Daily Mirror.
He reportedly ranted, "I'm not Joey. Don't you dare call me Joey. The papers say I'm finished so don't you call me f**king Joey. I want to leave that all behind. I'm moving on... I'm not Joey. For the last time. I'm not f**king Joey. It's Matt. Matt LeBlanc. Joey's in the past. I'm trying to do something new."
In a recent interview, LeBlanc insisted he didn't mind still being linked with his famous Friends alter-ego, saying, "If people really believe me as that character, I have done my job. I don't look on it as a negative thing. I take it as a compliment."