The movie version of The Da Vinci Code, starring Tom Hanks, was a box office smash in 2006, grossing more than $758 million (£505 million) worldwide. A successful follow-up, Angels & Demons, was released last year (09).
Brown's latest bestseller, 2009's The Lost Symbol, has also received the green light from movie bosses at Columbia Studios to be transformed for the big screen, and Eastern Promises writer Steven Knight was hired to pen the screenplay.
However, Brown himself has now taken over writing duties and will come up with the script for the movie, according to The Hollywood Reporter.
Brown, who acted as an executive producer on The Da Vinci Code, has not had any input into the previous films' screenplay - Akiva Goldsman wrote the first and shared duties with David Koepp on the second.
It is not known why Knight is no longer involved with the project.