The film, which satirises Christian fundamentalism, has attracted the wrath of officials at the infamous Westboro Baptist Church in Kansas, who will picket outside the premiere.
In a strongly-worded press release, the church leaders claim Red State mocks "the servants of God" and they have branded Smith "a hater of Biblical proportions".
They've also attacked film festival founder Robert Redford and his Sundance directors for "enabling perverts at the Sundance Film Festival".
Publicity-loving Smith couldn't be happier - and he hopes to add to the chaos in Sundance on Sunday by staging his own protest, against the religious zealots.
The film is one of the highlights at this year's festival and Smith is planning to stage a public post-screening auction at the Eccles Theater for distribution rights to the movie.