The Clueless star died suddenly in December, 2009 after suffering a cardiac arrest at her California residence.
Murphy's devastated mother Sharon, who lived with the couple at the mansion, put the house on the market in March 2010 - only to remove it from sale a month later (Apr10).
The family was hit with another tragedy when Murphy's husband Monjack passed away weeks later in May (10). Bizarrely, both husband and wife died of pneumonia combined with anaemia.
Now Sharon Murphy has decided to move away from the bad memories and is set to put the house under the hammer in an auction at a courthouse in Pomona, California.
According to TMZ.com, court documents show there is still over $4 million (£2.6 million) owed on the house, which fetched an asking price of $7.25 million (£4.8 million) last year (10).