The royal drama, about stuttering British monarch George VI, won the Best Drama prize and Performance Of The Year for its star Colin Firth. It also landed the Special Recognition prize, for an outstanding movie performance.
Accepting the prestigious award from Gwyneth Paltrow, director Tom Hooper told the crowd at London's Wembley Arena, "Of all the people who have presented me awards, I'm particularly grateful to Gwyneth for doing it tonight."
Simon Pegg and Nick Frost's film Paul landed Best Comedy, Disney's Tangled won the Best Animation prize, while Harry Potter and the Deathly Hallows: Part I took home Best Fantasy.
The second part of the wizarding story, Harry Potter and the Deathly Hallows: Part II, which marks the end of the film franchise, was named Must See Movie Of The Summer, while one of its stars, Jamie Campbell Bower, landed the coveted One To Watch: Brits Going Global prize.
Johnny Depp was also honoured at the event, landing the Screen Icon prize. In a taped video message, he said, "I would like to thank all of you... for this amazing, sublime honour of the Screen Icon award. I'm not so sure I'm worthy, but thank you."