Jolie will play the legendary leader in David Fincher's re-telling of the famous story, which is set for release in 2013 on the 50th anniversary of the classic original movie starring Elizabeth Taylor.
And the Tomb Raider actress is adamant her version of the raven-haired queen will be far less glamorous than Taylor's infamous portrayal.
Jolie tells Britain's Stella magazine, "She has been very misunderstood. I thought it was all about the glamour, but then I read about her and she was a very strong mother, she spoke five languages and she was a leader.
"My performance will never be as lovely as Elizabeth's. We are trying to get into a different truth about her as a pharaoh in history and not a sex symbol, because she really wasn't. Even this idea of her having many lovers - it was possible that it was only two. She is very interesting, but she wasn't a great beauty."