Baron Cohen revealed that the event organizers decided to give Depp the special award after realizing more people had voted for him in the past 10 years than any other celebrity.
Meanwhile, Bullock was named Favorite Movie Actress, and her film The Proposal won the Favorite Comedy Movie prize.
Laurie claimed the Favorite TV Drama Actor honor for House, which picked up the night's Favorite TV Drama award.
Over 60 million film fans, music lovers and TV viewers voted for the awards.
The winners were:
Favorite Talk Show - The Ellen DeGeneres Show
Favorite Comedy Movie - The Proposal
Favorite R&B Artist - Mariah Carey
Favorite TV Comedy Show - The Big Bang Theory
Favorite TV Drama - House
Favorite TV Drama Actor - Hugh Laurie (House)
Favorite Movie Actress - Sandra Bullock
Favorite Movie Actor - Johnny Depp
Favorite Action Star - Hugh Jackman
Favorite Independent Film - Inglourious Basterds
Favorite Breakout Movie Actor - Taylor Lautner (New Moon)
Favorite Male Artist - Keith Urban
Favorite Female Artist - Taylor Swift
Favorite Country Artist - Carrie Underwood
Favorite Web Celeb - Ashton Kutcher
Favorite New TV Drama - Vampire Diaries
Favorite New TV Comedy - Glee
Favorite Movie Actor of the Decade - Johnny Depp
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