The siblings received nods in the Favourite TV Actor category for their roles in Disney show Jonas - but face tough competition from twins Cole and Dylan Sprouse, who star in The Suite Life on Deck.
Disney queen Miley Cyrus is up against her pal Selena Gomez (Wizards of Waverly Place), Miranda Cosgrove (iCarly) and Keke Palmer (True Jackson, VP) for the Favourite TV Actress award - but her hit series Hannah Montana has been sensationally snubbed in the Favourite TV Show category.
Gomez and Cosgrove's shows will fight it out for that honour, along with Sonny with a Chance and The Suite Life on Deck.
Cyrus dominates the music categories - picking up nods for Favourite Female and Favourite Song for Party in the USA. The track goes up against I Gotta Feeling by the Black Eyed Peas, Paparazzi by Lady Gaga and Taylor Swift's You Belong with Me.
The teen sensation, Swift and Gaga face R&B superstar Beyonce in the Favourite Female category, while Jay-Z, Sean Kingston, Mario and Ne-Yo are all in the running for the Favourite Male nod.
The Black Eyed Peas and the Jonas Brothers picked up one further nod each - for Favourite Music Group. They'll face British band Coldplay and rockers Linkin Park.
It's the battle of the movie hunks in the Favourite Actor category - Zac Efron (17 Again) will face off against Taylor Lautner (The Twilight Saga: New Moon), Shia LeBeouf (Transformers: Revenge of the Fallen) and Tyler Perry (Star Trek).
In the actress category, Cyrus receives a nod for Hannah Montana: The Movie and is up against Sandra Bullock (The Blind Side), Megan Fox (Transformers: Revenge of the Fallen) and Zoe Saldana (Star Trek).
Action blockbusters Transformers: Revenge of the Fallen and X-Men Origins: Wolverine are up against fan favourite The Twilight Saga: New Moon and kids' classic Alvin and the Chipmunks: The Squeakquel for the Favourite Movie accolade, while Up, A Christmas Carol, Ice Age: Dawn of the Dinosaurs and Monsters vs. Aliens are all in contention for the Animated Movie award.
Monsters vs. Aliens stars Reese Witherspoon and Seth Rogen are both nominated in the Favourite Animated Movie Voice category, along with Jim Carrey (A Christmas Carol) and Ray Romano (Ice Age: Dawn of the Dinosaurs).
The Kids' Choice Awards take place in Los Angeles on 27 March (10).