The Mighty Aphrodite star has only made a handful of movies and TV appearances in recent years, preferring instead to spend time with her husband, Christopher Backus, and their three children.
And Sorvino admits she has missed out on some "intriguing" acting work to ensure she is at home while her kids grow up.
She tells Parade magazine, "I don't want to take time away from my kids. I used to work all year long and basically live in hotel rooms. Kudos to women who can pull that off, but I don't want my kids raised by nannies. I have the best children and husband. I'm really, really blessed.
"I've made many professional decisions where I've been offered pretty intriguing situations both financially and career-wise. But they just required being away from home and I couldn't be without my children.
"My mother was a stay-at-home mum. She was amazing, always there for us. Somewhere I guess there is a middle ground, but you see your kids suffer when you leave them with someone else."