The Oscar-winning star was presented with the prize at the Beverly Hills event by movie mogul Harvey Weinstein.
An emotional Zellweger told the Beverly Hilton Hotel audience, "I didn't expect this to be such an emotional experience. Now my fake eyelashes are going to fall off."
Something's Gotta Give director Nancy Meyers picked up the Dorothy Arzner Award, and Steven Spielberg presented his longtime producer Kathleen Kennedy with the Paltrow Mentorship Award, in honor of Gwyneth Paltrow's late producer father Bruce.
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