The Hollywood Foreign Press Association will honor Spielberg at the event on Jan. 13.
The Cecil B. DeMille Award is usually given to actors and actresses for their "outstanding contribution to the entertainment field."
The six-time Golden Globe winner and 12-time nominee will join Warren Beatty, Anthony Hopkins, Robin Williams, Michael Douglas, Gene Hackman, Harrison Ford, Al Pacino and Barbra Streisand as the recipients of the honor since 2000.
Nominations for the 65th Annual Golden Globe Awards will be announced on Dec. 13.
The role of Miss Golden Globe is given to the daughter of a well-known celebrity each year; Jack Nicholson's daughter Lorraine filled the position earlier this year.
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