Former stars including George Clooney, Julianna Margulies and Noah Wyle are returning for the final season of the long-running hospital drama, which will wrap with its last episode airing in the U.S. on April 2.
But network chiefs at NBC are plotting to keep the spirit of the show alive, with a new series centred around Stamos' character Dr. Tony Gates.
A source tells the National Enquirer, "This spin-off is the network's secret weapon, and they're hoping it will draw a new generation of viewers. Everything's under tight wraps. The script is still untitled and is being worked on as The John Stamos Project."
(c) 2009 WORLD ENTERTAINMENT NEWS NETWORK LTD. All global rights reserved. No unauthorized copying or re-distributing permitted.