The beloved funnywoman had held on to the prize since 2005, but faltered at the ceremony on Sunday when she came up against The View's feisty foursome Whoopi Goldberg, Joy Behar, Elisabeth Hasselbeck and Barbara Walters.
But it wasn't all bad for DeGeneres -- her daily talk show pulled back by picking up four awards during the night.
Haskell was also celebrating after her show scooped the most awards of the night, tied with All My Children -- winning five Emmys in total.
PBS' Sesame Street received the lifetime achievement award in recognition of its 40-year run.
(c) 2009 WORLD ENTERTAINMENT NEWS NETWORK LTD. All global rights reserved. No unauthorized copying or re-distributing permitted.