Charles died of complications from lung cancer in Los Angeles on Wednesday (03Aug11).
According to TMZ.com, she was diagnosed with the condition just a few months a go.
A family member says, "Annette had recently started having difficulty breathing... and when she went to the doctor she learned that she had a cancerous tumour in her one of her lungs."
The actress landed her first role in 1968 with an appearance on U.S. TV show The High Chaparral and she later guest starred on a number of popular series, including The Bionic Woman, Patrick Duffy's The Man from Atlantis, The Mod Squad, and Magnum, P.I.
However, Charles is perhaps best known for her role as Cha Cha DiGregorio in movie musical Grease.
Hoy, best known for his adrenaline-fuelled shoots with horses in western movies Bonanza and The High Chaparral, passed away last week (08Feb10) after a battle with cancer.
Performing stunts until he was in his late 70s, Hoy appeared in more than 150 films, including Spartacus and The Defiant Ones.
He went on to set up the Stuntmen's Association of Motion Pictures, which represents those working in the stunt industry.
Hoy is survived by his wife Kiva and a son, Christopher.