Dr. Doug Hanson brings on a new partner, Dr. Jonathan Seger. Dr. Holland helps a man who keeps getting lost. Dr. Hanson operates on talented young musician who has a brain tumor.
A pregnant woman refuses radiation treatment for her brain tumor in order to protect her unborn child, but has a surgery that could prolong her life. The surgery causes her to lose control of the left side of her body. But she is still able to write and type with her right side, leading Doug to an alternative to radiation. Meanwhile, Jonathan gets himself in trouble by speculating on a patient to the patient's lawyer.
Hanson operates for a second time on a patient, but he must stop her heart to do it and her brother is against the operation. Meanwhile, Adrianne falls for a patient who she has diagnosed with face-blindness.