The case of an accused serial killer in Australia takes a turn for the bizarre when one of his presumed victims walks into the courtroom.
A husband and father was the prime suspect in the murder of his wife for 18 years until the true murderer was discovered to have been the BTK killer.
The murder of a 53 year-old wife and mother is at first thought to be a carjacking and robbery until the police home in on her husband as a suspect.
A man goes to trial for a third time to defend himself against charges that he stabbed his wife to death.
The brutal murder of a Texas real-estate agent who lived a life on the edge that included gambling, prostitutes and substantial financial debts is examined.
An Ohio police officer comes under suspicion that he arranged his wife's murder in an effort to become the police chief.
Jeffrey MacDonald, a former doctor convicted of killing his family speaks to 48 Hours Mystery as new evidence comes to light that may prove his innocence 25 years after he was imprisoned.
48 Hours Mystery delves into the murder of a prominent doctor's wife.
In a story that could be the plot of a horror film, two young women are stabbed to death on Halloween night in Napa Valley leaving the police with few suspects.
A new suspect is discovered in the 30-year-old mystery of a young woman.
A woman's disappearance is credited to her husband, who claims that she packed her bags and left on a vacation.
Four students crack the case of the murder of a newlywed couple who were stabbed to death in 1986.
The actual location and circumstances of Jesus Christ's birth are examined.
A detective refuses to quit the case until the identity of a murdered teen found stuffed in a garbage bag is discovered.
The FBI spends ten years trying to discover the truth behind a dynamic college girl's disappearance.
A bodybuilder with an appetite for steroids turns into a wanted man when a love triangle leads to murder.
A 13-year-old babysitter is charged with the murder of the infant she was taking care of.
A young man confesses to a murder after dreaming that he committed the crime.
A fairytale romance sours when 25-year-old woman's Italian husband kidnaps their baby and takes her from Los Angeles to Italy.
A young woman vanishes without a trace after a night of gambling alone at a casino.
Two wealthy brothers in a web of gambling, secrets and lies become suspects in a murder mystery involving the bookie's wife.
Deputy of Police Gerold Dompig, Arubas lead investigator into Natalee Holloway disapearance believes that the young Alabama woman was not murdered but died from possible alcohol and drug related incidence. 48 Hours Correspondent Troy Roberts sits down with Dompig as he candidly talks about his theories.
A honeymoon turns into a mystery when George Smith disappears from a cruise ship.
19 years ago a young banker, David Harmon was beaten to death in his own bed. At the time police had questions about his wife's story that two men broke into their house intending on robbing the bank were he worked at but didn't have enough evidence. New evidence points to the now widow, Melinda as being involved in the brutal murder.
New documents and interviews raise even more questions about the night Marilyn Monroe died.
After two years of marriage, Stephanie Pepper Sims, a Louisiana Tech University Professor who grew up in Jonesboro, LA a small town and her husband David Sims a successful accountant were getting separated.
A young dancer's dreams of fame on Broadway are cut short when she's murdered.
Did a jealous husband kill a country music star? Randy Hardison, well known in the Nashville country music world, singer songwriter, musician, was found lying in a pool of blood one morning in Nashville.
Richard Davis, 25 year old Army Specialist survived the dangers of Iraq, bombs exploding all around him, bullets flying within inches of him and comrades only to make it back to the States to be murdered.
What caused mild mannered Carl "Charlie" Brandt to brutally kill his niece and wife and then hang himself? Police arrived on the scene after friends and family had not heard from Micheal Jones, 37 years old, successful and well loved.