When a police detective-turned-private investigator falls in love with a romance novelist who also happens to be a 450-year old vampire and the bastard son of Henry VIII, it complicates not only her job but her relationship with her mortal boyfriend.
Vicki is attacked by a zombie as she tries to find out why, she learns that a voodoo priest has put a death curse on her.
A young girl with telekinetic powers is controlling a demon. Henry and Vikki have to help fight the demon. Meanwhile, Mike doesn't trust Henry and wants to find out more about who he is.
Mike is upset with Vicki for not telling him that Henry is a vampire. Meanwhile, a vengeful spirit and a witch target someone close to Vicki and Mike.
A man hires Vicki to find out if his wife is cheating on him. When she and her lover turn up dead in their home, the police suspect Vicki's client. Vicki must find out who really murdered the wife.
A homeless woman comes to Vicki for help when her homeless friends keep disappearing. Meanwhile, Mike is working a case where a hooker's blood has been drained and Mike suspects Henry.
Mike inadvertently helped a man from Henry's past capture him and now Mike and Vicki must find where the man has taken Henry in time to save him.
Vicki is still upset with Mike, but concerned when she learns he may be involved with a dangerous woman. When a male model goes missing, Vicki and Henry search for Medusa, the gorgon of Greek lore, and turn up many more men that have been turned to stone. Vicki must slay the gorgon and save the lives of the men.
When a body of a dead boxer disappears from the embalming table, the funeral director calls in Vicki to find the missing body. He shows her the tape of a man coming in and the boxer getting up off the table and walking after him.
A man hires Vicki to find his wife who is went to a clinic that promised to help her get pregnant. Now they won't let the man have contact with her. Vicki convinces Mike to go undercover with her so they can determine if the clinic really is a cult as the man believes.
Norman returns and is after Vicki. He needs three things to make it happen--a book, a sword and chalice. Henry tries to help Vicki prevent Norman from obtaining these items. Meanwhile, Mike works with a new partner trying to solve some mysterious murders that are related to Norman's plan.