Bethany Horowitz asks Alan Shore to help her out with a case against a large tobacco company. But when it turns out that the defense attorney is Phoebe Prentice an old flame of Alan's, he finds himself distracted and fears that he won't be able to perform in court. Meanwhile, Denny is distraught over his own personal lack of performance in the bedroom.
After Denny Crane almost dies from toxic shock due to his unintended misuse of an arsenal of prescription drugs, Alan Shore takes on a pharmaceutical company for employing deceptive advertising to scare people into using their products.
Denny Crane is arrested yet again for carrying a concealed firearm after he shoots a man in self defense who's attempting to mug him and Jerry Espenson. Meanwhile, Alan Shore fights for a sex surrogate's right to joint custody of her daughter -- while grappling with the fact that he was a former client of hers.