Willows investigates the murder of a stripper at the Palermo; Stokes and Sidle investigate a body found out in Area 51; Grissom shows Sanders the ropes as they investigate a club shooting; Brown investigates a man electrocuted in a bathtub; Sanders shows his new lab replacement around the office.
While searcing the city's drains and sewers for evidence on one dead body, the CSI team finds the skeletal remains of a young boy as well.
A young girl goes missing and an amber alert is issued; the CSI team starts looking at a registered sex offender as a suspect.
Willows is called to the scene when a woman is found with lesions resembling Ebola. After the autopsy, the lesions are found to be the result of cosmetic surgery. Grissom and the rest of the team investigate the death of a homeowner found in his house post exterminator fumigation.
The CSIs delve into the world of swingers when a woman is found dead within the vicinity of a group's party. Catherine asks for a promotion. Warrick and Nick work a bloody murder only to discover that they had more victims than they originally thought.
After a body is found in a field of maggots on a college campus and blood stains turn up in a woodchipper, evidence leads Grissom to realize that the murders are the work of the Blue Paint Killer.
Grissom works with the CSI day team to investigate an abduction from a high school dance.
The CSI team investigates the brutal stabbing of a transgender woman.
Grissom gets new evidence while testifying in the case of a murdered restaurant owner. Due to the court proceedings, the case has to be re-opened. Even though they put the correct killer behind bars, the new head of the department splits up the team.
At the crime scene of a 16-year-old kid shot to death during an apparent drug deal, Greg finds the emaciated dead body of a young boy in a nearby alley. When the brother of the teenage victim arrives on the scene and swears revenge to Grissom, more shots are fired and pandemonium breaks out.
The CSI team looks for the killer of a Sherlock Holmes enthusiast who has been murdered in his perfectly recreated Victorian study.
When the decapitated head of a woman is found, a snake shoved down her throat, in a newspaper dispenser, the CSI team ends up investigating the dark underworld surrounding a mariachi band.
After the bodies of two women are found at a construction site, the CSI team must investigate the world of Russian mail-order brides.
A woman disappears after going with her friend to a bar and the investigators discover that she was killed by her boyfriend and step-mother for her inheritance. The bodies of a hunter and a bear are found on the outskirts of Las Vegas. The CSI detectives start an investigation into a possible third party that may have killed both.
A major casino owner is found dead in his driveway causing both CSI teams to investigate.
The CSIs hunt for a murderer at a convention for overweight adults.
Grissom and the team use new technology to process a fingerprint in the hopes of catching a serial killer.
A connection is found between a fire in the Las Vegas Wilderness and the slaughter of an entire family in their home.
The CSIs simultaneously investigate four different cases involving a Hummer, a bodybuilder, a model and a boy found on a bench.
Captain Brass travels to Los Angeles and seeks the aid of a former colleague when his estranged daughter's friend disappears.
Grissom and Sarah investigate the murder of a patient in a mental hospital.
A case becomes personal for Catherine when a man she flirted with at a bar turns up as a murder suspect.
The CSIs are immersed in college life when two amorous students are found dead in a dorm room.
The CSIs race against time to rescue Nick who has been kidnapped and buried alive by a man seeking revenge for the imprisonment of his daughter. The investigation becomes a game of cat and mouse as he leaves deliberate clues for them to follow while Nick must deal with the confined space, lack of air and an invasion of fire ants who threaten to eat him alive.