As the celebrity patients check in, Dr. Drew meets with each of them one-on-one. First to arrive is actor Gary Busey, then Amber Smith, Rodney King, Tawny Kitaen, Guns 'n' Roses drummer Steven Adler, Sean Stewart, Nikki McKibbin and Jeff Conaway. Gary Busey informs Dr. Drew that he is "not here seeking treatment," but is instead expecting to act as an addition to Drew and his staff.
First, Gary Busey is feeling insecure about his place amongst the patients, so Dr. Drew sets up a meeting with psychiatrist Dr. Sophy. Meanwhile, several of the patients are detoxifying from the dangerous drugs on which their bodies have become dependent.
First, Rodney King addresses the guilt he feels at not being a continuous part of each of his three daughters' lives. Next, Sean Stewart realizes he struggled with feeling abandoned whenever his famous father, Rod Stewart, would go on tour.
As the midpoint draws near, the patients at recovery center, start facing tough emotional issues, while exploring what is behind their addictive behaviors.