"Operation: P.O.P." "P.O.P." stands for "Pre-teens Oppose Prohibition." When the drinking age of sodas is raised to thirteen, Numbuh 2 is arrested for brewing illegal soda for sale.
"Operation: S.P.A.N.K." "S.P.A.N.K." stands for "Sore Posteriors Annoy Naughty Kids." Having just been released from prison for having illegally spanked an innocent child, Count Spankulot vows to help children.
"Operation: S.U.P.P.O.R.T." "S.U.P.P.O.R.T." stands for "Special Underwire Protection Purportedly Outfits Rotten Teenagers." When Numbuh 5 gets sick, Numbuh's 1 and 2 go to her house to protect her from the chance of people stealing top secret information from her.
"Operation: M.O.V.I.E." "M.O.V.I.E." stands for "Meeting Of Villains Isn't Entertaining." Numbuh 4 hates the kiddie movies that he attends with the Kids Next Door, so tries to get into a Rated R movie only to find out that the movie is really a place for villains to meet.
"Operation: S.H.A.V.E." "S.H.A.V.E." stands for "Southern Hair Attacks Virtually Everyone." Numbuh 142 is found sporting sudden mustaches, claiming many operatives are succumbing to facial hair.
"Operation: F.L.A.V.O.R." "F.L.A.V.O.R." stands for "Find Lost Ancient Variety Of Refreshment." Numbuh 5 goes on a journey to find the fourth mythic flavor of ice cream that has been hidden away for centuries.
"Operation: G.H.O.S.T." "G.H.O.S.T." stands for "Ghostly Hamsters Overwhelm Spooky Treehouse." Chubbo the hamster's death causes Numbah Three to maintain a vigil at the hamster's grave.
"Operation: T.H.E.-S.H.O.G.U.N." "T.H.E.-S.H.O.G.U.N." stands for "Terribly Huge Enemy Steals Heaps Of Gorgonzola Using Ninja." The Kids Next Door try to stop the cheese shogun who has stolen all the cheese from the new All-Cheese Restaurant.
"Operation: R.E.P.O.R.T." "R.E.P.O.R.T." stands for "Ridiculous Exaggerations Possess Occasional Real Truth." The Kids Next Door each tell different versions of the same story about rescuing important materials from the Kids Down The Lane.
"Operation: C.A.K.E.D.T.W.O." "C.A.K.E.D.T.W.O." stands for "Commandoes Attempt Kapturing Enemy's Dessert - They Weren't Obliging." The Kids Next Door try to get to The Kids Down The Lane's annual birthday cake, but it proves more difficult than they thought with the villains escape thanks to cleverly placed holograms.
"Operation: B.E.A.C.H." "B.E.A.C.H." stands for "Boys Enthusiastically Attempt Chivalrous Heroics." While on the beach, Numbuh 3 is captured by knights after building a sand castle in their territory.
"Operation: D.O.G.F.I.G.H.T." "D.O.G.F.I.G.H.T." stands for "Dueling Over Gooey Frankfurters Invariably Gives Hoagie Trouble." Ace pilot Numbah Two is blown out of the skies by another child and warned not to fly again.
"Operation E.N.D." "E.N.D." stands for "Everyone Nearly Decommissioned." Numbuh 1 is mistakenly set for decommissioning and memory erasing by global command, despite the fact that he is much younger than thirteen.