The Joss Whedon series about agents for hire who receive personality implants for each mission---and have their memories cleared once finished---opens with Echo (Eliza Dushku) becoming a hostage negotiator in order to free a kidnapped girl, the daughter of a businessman (Kurt Caceres) who'd rather pay big bucks than go to the police. Meanwhile, an FBI agent (Tahmoh Penikett) finds his career threatened by his search for the illegal Dollhouse. Dr. Claire Saunders: Amy Acker.
Echo becomes the target of an expert outdoorsman's hunt after she's imprinted with a persona to match his. Agent Ballard's investigation, meanwhile, is boosted by information concerning Echo's true identity. Richard O'Connell: Matt Keeslar.
Echo provides protection to a pop star by becoming her backup singer. Ballard's investigation, meanwhile, takes a wrong turn that may prove dangerous; and Lubov has a secret.
Echo's stint as a safecracker doesn't go as planned, causing Sierra to be imprinted with a familiar persona. Meanwhile, Ballard delivers an ultimatum to Lubov, and Adelle shares shocking information with Topher.
Echo infiltrates a dangerous cult in order to save a woman who's being held against her will, but the mission may be complicated by the imprint given her: that of a visually impaired woman.
Echo is turned into a model wife for an Internet mogul (Patton Oswalt); the identity of Sierra's attacker is learned; Mellie's life is endangered; Ballard comes face-to-face with Echo.
Echo returns to school when a college campus is threatened by the outbreak of a deadly virus. At the same time, parts of her previous life are brought into focus.
After she, Sierra and Victor awaken in the Dollhouse as their original selves, complete with their own memories, Echo leads the Actives in an escape attempt. Ballard, meanwhile, learns more about the location of the Dollhouse.
Echo and Sierra are turned into spy hunters in order to track down a Dollhouse traitor. Meanwhile, Mellie delivers surprising news to Ballard; and Adelle has a secret.
After a friend of Adelle's is slain, Adelle has Echo programmed with the dead woman's memories and personality in order to find the killer. In other events, Ballard investigates Mellie's past and Topher imprints Sierra for a secret engagement.
Alan Tudyk guest stars as the Dollhouse designer, who finds himself the focus of Ballard's investigation. Meanwhile, Echo helps a young girl cope with her painful past; Adelle searches the attic for answers; and Alpha reveals himself.
The Season 1 finale finds Alpha's Echo obsession growing ever more dangerous, Ballard's search for the Dollhouse coming to a conclusion, an Active being permanently deactivated and another's surprising past coming to light. Stephen Kepler: Alan Tudyk.