Captain Hero comes face to face with a mentally handicapped giant terrorizing the city. He soon learns that this Giant is, in fact, his son and the mother is his own sister, Captain She-Ro. Meanwhile, Princess Clara develops Munchausen's by Proxy and is rewarded for her care of a sickly Wooldoor, whom she alternatively heals and injures as a result of the syndrome.
Captain Hero thinks their new neighbors -- a family of Greek immigrants -- are actually a fraternity. Meanwhile, Toot marries Ling-Ling's sick father in order to get her chubby hands on his money -- Ling-Ling's inheritance.
When Congress decides to let Wooldoor's new kids program go on the air despite concerns that it will turn kids gay, a Terminator arrives from the 'gay future' on a mission to kill him and guarantee a 'straight future.' Meanwhile, Toots eagerly awaits the arrival of the Weiner Mobile, but misses her opportunity when she's locked in the closet.
A spelling bee conjures up distant, but painful, memories in Foxxy, but Spanky does everything he can to convince her to compete in it because of the prize: an Applebee's gift certificate. Meanwhile, Captain Hero woos Clara after she successfully protects him from a homeless man at the grocery store.
Captain Hero goes commando when the house is robbed and ends up hunting animals with assault weapons. A little deer convinces him to give up his efforts, so, he commits to ridding the world of assault weapons. Meanwhile, Foxxy hides her grandson in the walls of the house, enabling him to see the housemates' activities. The young boy soon falls in love with Toot and her ghetto booty.
Captain Hero neglects his responsibility to protect the Earth as a giant asteroid heads toward it all because he can't be one of the "cool kids," comprised of Foxxy, Princess and Ham. Meanwhile, Toot and Ling-Ling enter a cockfighting league in order to earn enough money to keep themselves out of Mexican jail.
Princess Clara fears the Apocalypse is nigh after taking account of her roommates' behavior. So when the group excludes her from a field trip to the mall, she awakens to find an empty house and assumes the worst.
Toot drinks saltwater and goes insane, prompting the others to kill and eat Ling-Ling.
Spanky Ham has a one night stand with a spider which leads to trouble. Captain Hero faces his nemesis and they come to an understanding. Meanwhile, Ling-Ling's violent tendencies are explained.
Wooldoor becomes the mascot for Quackers cereal after the original mascot dies under mysterious circumstances.
The Drawn Together Babies live together as tiny children.
Ling-Ling overdoses on his 21st birthday. Hero learns that he has the ability to communicate with his younger self.
Wooldoor hypnotizes Foxxy to try to discover why she is so promiscuous. Meanwhile, the housemates tease Toot until Xandir offers to help Toot change her look.
The house mates find themselves in a competition as they look back at the highlights from the season.