A behind-the-scenes documentary about the filming of "Medellin" on location in Bogota, Colombia. On the set, Eric and Billy clash over keeping the film on schedule and Billy develops an infatuation with Vince's beautiful Colombian co-star that becomes increasingly disruptive to the production. Meanwhile, Drama tries to angle for a part in the film, and Ari provides color commentary from his LA office.
Drama plans a welcome-back party for Vince at his new condo, but his obsession with keeping the place pristine puts a damper on the festivities. Ari and his wife learn that their son may not get into their daughter's exclusive school and upon investigation discover that it's because of Ari.
Vince and the guys crash at Drama's. Donna Devaney, a girl from Drama's past has finally agreed to hook up with him and has a friend for Turtle. Eric tries to give Walsh some notes to fix up the film, but Walsh isn't interested in his help and has already sent the print to the Cannes Film Festival.
Eric must give bad news to a Hollywood big shot. Meanwhile in an attempt to get annexed to 90210, Drama takes the mayor of Beverly Hills out for a night of fun. Ari gets himself in trouble with a top-secret script.
The 'Medellin' trailer ends up on YouTube and Billy is furious and blames Eric. Drama tries to appear younger by getting a prescription for a medical-marijuana facility. He wants to purchase the club's stylish cap. Meanwhile, Ari and Lloyd try to sabotage a deal so that Vince can get his next project.
Ari finally gets Vince a job on 'Lost in the Clouds' but E threatens to derail it because he wants Walsh off the picture. Ari gets Walsh and E to his office to make peace.
When E catches the eye of a waitress, Drama brings up the fact that E can't have sex without pursuing a relationship. Drama bets that Turtle can have a one-night stand before E.
Eric gets an office and as a gift, the guys find an antique desk that has some Hollywood history attached to it. They are upset to learn that it's been sold to another actor already, especially when they learn who the actor is. Meanwhile, Ari prepares for his annual meeting with one of his clients, but has to deal with some office drama first.
When Eric gets in a fender bender with Anna Faris he believes that they "shared a moment." Meanwhile, Turtle picks up supplies and women for an afternoon party, but gets sidetracked on the way home. Mrs. Ari is asked to reprise her role on a "Y&TR" anniversary special, to Ari's chagrin.
Ari receives Billy's script for Vince's next project, but Billy's version is very different from the adaptation he was supposed to write. Ari tries to keep the studio interested in the project now that the concept has changed. Eric deals with domestic issues between his new client and her boyfriend.
The guys are delayed on their way to Cannes for the "Medellin" when there is a code orange at LAX. Ari deals with Mrs. Ari and Lloyd who both want to come along for the trip. Billy works Eric's new client into his script. However, Eric's new client and Vince are both upset with Eric.
At Cannes, the guys party it up and attend to the business of selling "Medellin," a not-so-easy task, since the finished film has yet to be screened. Meanwhile, Drama benefits from the overseas popularity of "Viking Quest."