Monk searches for his wife's killer in New York City.
When a music producer is found dead with bullets in his back -- and his pet chimpanzee is caught with the murder weapon in his hand, Monk is called in to investigate.
A bomb is detonated in San Francisco power plant and Monk is called in to investigate.
In order to regain his detective license, Monk must find evidence to help capture a murderer.
Monk infiltrates an organized crime family to get to the bottom of an apparent mob hit.
The sight of a blood-soaked man has Sharona questioning her sanity.
When an employee of the local Mega-Mart is killed by a falling television set, Monk is called in to investigate.
Monk visits Los Angeles to help his father-in-law determine if a game show contestant is cheating.
Monk takes medication that alleviates the symptoms of his obsessive-compulsive disorder but hinders his ability to solve crimes.
Monk tries to help single mother Natalie Teeger discover why people are breaking into her home after she kills an intruder in self-defense. In the process of his investigation, Natalie takes over as Monk's new assistant.
Monk tries to figure out how a person supposedly dead over six years could have committed a recent murder.
After being witness to a Chinese mob killing, Monk is sequestered in the woods by the police. But while staying in a remote cabin, he witnesses another murder.
Monk, Natalie, and Julie get stuck in a traffic jam while on the freeway. While stuck, Monk realizes that the accident that caused the traffic jam was probably a murder.
While in Las Vegas, Stottlemeyer attends a bachelor party that results in a possible murder of a wife by her casino owning husband. Monk arrives to investigate and quickly gets the case solved.
Natalie is shot at while preparing for her upcoming school board election and the prime suspect is Howard Krenshaw, one of Dr. Kroger's other patients. But when Monk realizes Krenshaw is innocent, he starts to figure out who might have had the motive.
Monk tries to help find the body that belongs to a missing finger found by a twenty-two-month-old named Tommy. While investigating the case, Monk develops a fondness for the young child, who has been in and out of foster care.