Josh Gould returns with a degree from Oxford to teach sexual anthropology at the university. Josh's friend, Eric, really wants to get rid of his current fling, Sally, but she won't take his hints. Josh is thrown off by a fling with an Assistant Provost and his search for a place to live turns into a metaphor for his search for companionship. Natalie tries hard to be Josh's Research Assistant.
Josh runs into a big crush of his while out on a date set up by his mother. Natalie does some hands on research into "screw dates."
Eric's flirtation with Josh's new landlady lands him in trouble. Natalie debates her heterosexuality when it's believed she flirted with Jenn. Josh wonders what to do about Hunter.
Eric gets a very personal male piercing to impress women and finds himself in a physically enforced period of not trying not to think about sex. Josh investigates celibacy in an attempt to submerge himself in his work and finds himself attracted to a practicing stripper.
Josh has a hard time sexually with his tough, but sexy, karate instructor until he learns that she likes to play the submissive in the bedroom. Natalie has her hands full with a man who will do whatever she says. Eric feels challenged by a younger bartender.
One of Josh's ex's comes to town for a conference and Josh tries to put their painful past behind them. Eric tries to move into adult life by getting rid of his worn-down futon. Jenn worries that her girlfriend will fall back in love with an ex.
Josh starts to date two girls after he finds himself interested in both at a party. Eric has problems handling a relationship with a married woman.
Josh hooks up with one of Hunter's friends, much to her chagrin. Natalie's family reunion reveals a cousin that she's had a fling with in the past who wants to settle down with her. Eric is visited by the now very much grown-up girl he used to babysit.