Rae returns to San Fransisco and her husband from her volunteer work in Pakistan to find the Greek doctor she has a yearly affiar has joined the the medical group to be with her. The other doctors deal with a baby on the brink of death, a coach in need of heart surgery and an old man dying of cancer.
Despite Dr. Collete's distaste for treating burn victims, a firefighter convinces her to help his injured friend while Dr. Brennan tries to convince Dr. Kokoris to leave San Fransisco so she salvage her marriage.
Slingerland and Jordan discover a serious heart defect in a cable car worker while Keating looks for sperm donors amongst the doctors and the burn victim Keating treated has developed a crush on her.
A boy's parent's refuse to tell him he has a debilitating disease and Rae tries to intercede.
Singerland and Kokoris disagree on how they should treat a diabetic whose leg is in danger of being amputated.
When a little boy with bruises comes in for treatment, Dr. Keating suspects abuse and calls child services but may have jumped the gun. And a patient with severe heart problems clashes with his lover and son over his treatment.
After battling with Kokoris over how to treat a patient, a tough visiting surgeon tries to have him fired.
The hospital staff finds itself swamped with pregnant mothers delivering prematurely.
What with trying to save her deteriorating marriage and treating a girl dying of leukemia, Dr. Brennan deals with some difficult emotions.
Dr. Keating reaches out to a teen who may have tried to kill himself.