Janet and Tommy end the silence between them, months after the abrupt death of their son. Uncle Teddy, still stuck in prison, decides to remain there in lieu of accepting anyone's help for a release. Meanwhile, Tommy gets a big surprise when he learns that his sexually-active teenage nephew has been hooking up.
Franco and Tommy meet some women while on a guy's night out. Tommy tries to coax Colleen out of blabbing to Janet about the doting favoritism he showed Katy. Meanwhile, Jerry tries to get financial help from Lou in order to keep paying for the expense of his mother's pricey nursing home.
Tommy manages to put a stop to Damien's newfound "relationship" with his teacher, while Sean continues to try and keep his own sexual relationship a secret from Tommy. Meanwhile, Franco wishes to avoid ending up as Alicia's sex object, Chief Reilly copes with financial issues and Lou begins to lose a grip on his sanity.
The team raises the ire of Reverend Al Sharpton after taking on a children's school bus rescue en route to Harlem. Mike and his roommate have a frank talk about their sexual preferences, while Franco comes to understand Alicia's attraction to him. Meanwhile, Sean comes clean to Tommy about Maggie, while Janet decides to settle her differences with Tommy amicably, without legal assistance.
Tommy makes a move after Sheila inadvertently runs into Angie. Mrs. Turbody continues to be held on rape charges. Meanwhile, Jerry and Rose spend a cozy evening with one another, while Franco runs into a dire situation involving Keela.
Sean mistakes sleeping pills for painkillers after a rough street hockey game, and the pills have a dangerous effect on him. He also enlists Angie to help him mess with Janet's head by going out on a date. Meanwhile, Lou's uncle Red helps him get a better handle on the job.
Janet and Angie begin to grow somewhat closer as Tommy has another row with Johnny. Maggie makes another attempt to get Sean back, while Sheila fumes at the sight of Tommy and Angie. Meanwhile, Mike and Chris enter into some tensions over Chris' latest conquest and Franco learns about Jerry's need for supplementary income.
Sean and Maggie reach a turning point in their relationship. Lou tries to turn his life around with a spiritual side. Meanwhile, Tommy and Angie's ongoing relationship escalates and causes a bad run-in with Janet.
The crew gets more than they bargained for while trying to save a man from his burning apartment. Sean hopes to ask Maggie to marry him, but decides to ask Maggie's dad to give his blessing. Tommy fears for the future of the crew's unity. Meanwhile, Franco harbors suspicions about his latest girlfriend.
Tommy has a heated chat with Johnny after going to see Janet. He also continues to stay by Stack's side in his time of need. Meanwhile, Franco makes an effort to know the mentally-handicapped sibling of his new girlfriend, and Teddy is torn up by a disappointing visit with his daughter.
Tommy and John Sr. get into a verbal scuffle which ends with John taking off. Sean and Maggie ready for their marriage. Meanwhile, Jerry gets involved in a treacherous relationship and Tommy has issues with Lou's new girlfriend.
Tommy and Janet must come together once again to cope with another terrible personal event. Sean gets a shock from Maggie, and a soul-searching Mike looks for some real guidance about his sex life. Meanwhile, Jerry decides to ditch work.
Tommy keeps his plans with Sheila a secret from Janet, all the while offering to help Janet with the impending baby. Meanwhile, Franco looks in on his daughter.