Samantha teams up with her mother for a dance competition in order to beat Regina's nemesis, Paula Drake. The only problem is that "old" Sam could dance, whereas "new" Sam is gliding on two left feet. Meanwhile, Samantha wants to start enjoying her new, independent life alone in her apartment, but Todd is having trouble finding an apartment of his own.
In an attempt to find new direction in her life, Samantha suddenly decides to go to Africa and volunteer to help those in need. Her friends and family are convinced that she'll chicken out which she does after discovering the countless vaccinations and obstacles that she would face to make the journey. So to keep up the faade of being out of the country, Sam ends up hiding out with Andrea and Dena.
After Dr. Andy gives Samantha pills as part of a clinical trial to help people with memory loss, she begins to regain multiple memory fragments -- all reminding her of how bad she used to be. But she discovers one pleasant reminder from the past that could have changed her life forever. Meanwhile, when Andrea and Dena are mistaken for a gay couple, Andrea tries to prove that she could hook up with a much hotter woman than Dena.
Desperate for some cash and in need of a job, Samantha reluctantly agrees to team up with Regina and start a real estate business. But while Sam strives to stick to her path of morality, her handsome first client, Owen, could end up throwing her off course. Meanwhile, Andrea tries to seduce Todd's disheveled friend, Seth, in order to obtain the phone number of a professional basketball player.
After an altercation with a cop, Samantha is arrested and given community service, where she meets Natalie, a troubled young woman. Sam feels that it's her duty to help the wayward Natalie turn her life around, in spite of warnings from Andrea that Natalie's a bad seed who can't be turned. Meanwhile, even though Todd insists that they're just friends now, Howard offers advice on how to win back Samantha's affections.
After finally telling current boyfriend Owen that she lives with her ex-boyfriend Todd, Sam discovers that Owen's best friend is also his ex-girlfriend, Willow.
Sam's decision to invite boyfriend Owen for dinner to meet her parents turns into a disaster when Owen's philosophy about chicken farms rubs chicken farm owner Howard the wrong way.
Samantha struggles with trying to be the environmentalist she is not in order to impress philanthropist boyfriend, Owen. Meanwhile, Andrea discovers that she's not first draft in pro-basketball player Tony Danes' lineup for potential dates.
After getting her heart broken by a man she'd been dating, Sam goes on a family vacation with Andrea and Dena in tow and discovers that the owner of the lodge is an old flame from her forgotten youth. But not wanting to get her heart broken again, she resists the temptation of reconnecting with lodge owner Brad and then becomes jealous when Andrea makes a move on him.