The enigmatic Dr. Helen Magnus recruits insightful forensic psychiatrist Will Zimmerman to join her in the quest to track, study and protect the strange and often terrifying creatures that secretly populate our world.
Dr. Helen Magnus, her daughter Ashley, and the newest member to the Sanctuary, Dr. Zimmerman, travel to Northern Scotland to discover three women in an ancient crypt and bring them back to the Sanctuary for refuge and study.
While investigating a series of strange robberies, the Sanctuary team encounters a group of thieves, who seem to possess a strange ability which apparently allows them to literally slip between the cracks of the law.
While returning from a trip in Himalaya meant to capture an abnormal, Dr. Magnus and Will's plane crashes in a remote mountain range.
When two seemingly harmless abnormals arrive at the Sanctuary, the team finds themselves feeling some unusual animal attraction for one another.
When Magnus encounters an old acquaintance in Rome, he tells her that the Cabal is planning to seek revenge on her for the events of "Fata Morgana".