In the premiere episode, the cast performs sketches of current events. The sketches include, "A Non-Partisan Message from Governor Palin and Senator Clinton," "Quiz Bowl," "Jar Glove," "Swim Team Pep Talk," "Stacia and Cousin Craig," "The Charles Barkley Show," "T-Mobile," "Space Olympics 3022," "Mark Payne" and "The Michael Phelps Diet." Also starring Michael Phelps hosts and Lil Wayne performs live.
The cast performs sketches including "McCain Voice-overs," "The Cougar Den," "Agent 420," "Simpson Jury Selection," "Murray Hill," "The Looker," "New York Times Reporters," "Of Mice and Men," "Yankee Stadium Stories" and "James and Willam Dafoe." Also, Kings of Leon performed "Sex on Fire."
The cast members perform sketches including, "Sarah Palin Interview," "New Friends," "The First Presidential Debate," "Rowboat Date," "Scores" and "Deep House Dish." Also, Duffy performs "Mercy" and "Stepping Stone."
The cast members perform sketches, Anne Hathaway hosts and The Killers perform.
Sarah Palin and the cast perform sketches including, "Palin on Palin," "MacGruber," "Sue and the Engagement," "The Suze Orman Show," "Mark and Andy Backstage," "I'm No Angel," "Fart Face," "Narc School," "ReadiTrade.com," "New York Underground" and "Fall Foliage." Also, Adele performs "Chasing Pavements" and "Cold Shoulder."
The cast performs sketches including "Biden and "Murtha," "Pedophile Trick-or-Treater," "Ras-Trent," "Two A-Holes at an Ad Agency in the 1960s," "The Barack Obama Variety Half-Hour," "Don Draper's Guide to Picking Up Women," "Vincent Price's Halloween Special," "Jon Hamm's John Ham" and "Pat Finger." Also, Coldplay performs "Viva la Vida," "Lost," "Yellow" and "Lovers in Japan."
The cast performs sketches including "McCain/Palin on QVC," "Jar Glove," "The View," "Countdown with Keith Olbermann," "Target Greatland," "The Staten Island Zoo" and "Night School Musical." Also, David Cook performs "Light On" live.
The cast performs sketches including, "Joe Biden," "Sproingo," "Everyone's a Critic" and "Weekend Update." Also Paul Rudd hosts, and singing sensation Beyonce, performs new music from her upcoming album.
Tim McGraw hosts, and the cast performs sketches including, "Bond Casino Showdown," "Blizzard Man," "Weekend Update," "Rahm Emanuel" and "Turkey Day." Also, Ludacris and T-Pain perform live.
John Malkovich hosts, and the cast performers sketches including, "Secretary Clinton," "Gas Right," "Sexy Shannon," "Obama Keeps It Cool," "La Rivista Della Televisione" and "Virgania Horsen's Pony Express." Also, T.I. performs his new hit "Whatever You Like."
The cast performs sketches, actor Hugh Laurie hosts, and Grammy award wining singer-song writer-producer Kanye West performs.
The cast performs sketches including, "The Rachel Maddow Show," "Today," "Curtains for Broadway?," "Penelope in Group Therapy," "The Doogie Howser Orchestra," "Two First Names," "Air Traffic Control," "Frost/Other People" and "Whopper Virgins." Also, Taylor Swift performs.
The cast performes sketches including, "ABC News Special," "North American Savings," "Da' Learnin' Train," "Gitmo Clearance Sale," "Aladdin and Jasmine's 10th Anniversary" and "A Couple of Homies." Also, Rosario Dawson hosts and Fleet Foxes performs live.
Steve Martin hosts along with the original cast, which perform sketches including "Obama's Plan for the Economy," "Bernie Madoff's Super Bowl Party," "MacGruber" and "Socially Awkward Officemates." Also, Jason Mraz performs "I'm Yours" and "Lucky."
Bradley Cooper hosts along with the original cast, which perform sketches including "I'm on a Boat," "Today Show," "MacGruber" and "Sex With Your Wife." Also, TV on the Radio performs live.
Alec Baldwin hosts along with the original cast, which perform sketches including the "Republican Congressional Leadership Meeting," "The Fourth Jonas Brother," "The Cougar Den," "Property of the Queen," "Sir Mix-a-Lot's Photoshop" and "Vincent Price's Valentine's Day Special."
Host Dwayne Johnson and the cast perform sketches including "The Rock Obama," "Hawaiian Hotel," and "To the Lighthouse" as well as musical performances by Ray LaMontagne.
Tracy Morgan hosts along with the original cast, which perform sketches including the "Safari Planet," "Scared Straight," "Suppressex," and "The View" and Kelly Clarkson sings.
Seth Rogen and the cast perform sketches including "Muppet Bus," "Presidential Address," "Easter Album," and "Girlfriend Voice." Also, musical performances by Phoenix.
Zac Efron and the cast perform sketches including "Cool Bar," "Gilly-Science Fair," "I AM YOUR MOTHER," as well as the Weekend Update and musical performances by Yeah Yeah Yeahs.
Clips from Amy Poehler's sketches throughout the years including her portrayals of Hillary Clinton and Dakota Fanning.
Justin Timberlake hosts; musical guest Ciara performs. Sketches include the musical short, "Motherlover," the Target Lady, and "The Barry Gibb Talk Show." Leonard Nimoy appears.
Will Ferrell hosts, Green Day performs. Sketches feature George W. Bush and Dick Cheney, Celebrity Jeopardy, Weekend Update, and "Goodnight Saigon."